Use of microbial co-cultures is getting more and more important in many biotechnological processes, such as food biotechnology, plant biotechnology, production of fuels, fermentation, remediation, biofouling etc. It can improve the process or the final biotechnological product.
The problem:
The systems of co-culture are hard to optimize due to different growth dynamics of different strains and increased distances between cells when complex substrates are broken down to the level that is acceptable for use by microbes that produce desired substances.