Belgian SME offers services in the fields of pathology and digital image analysis

The Belgian SME offers an integrated solution to histological analysis as well as the identification, characterization and validation of tissue-based biomarkers. The methodology is based on standardized laboratory procedures and quality controls ensuring reproducibility and traceability. It involves the following technologies : (i) macroscopic analysis (organs, tissues, etc.), (ii) microscopic histological analysis (using haematoxilin-eosin and special staining), (iii) tissue microarray (TMA) and cell-block (for cell line analysis), (iv) immunohistochemistry (IHC), (v) whole slide imaging and image analysis, (vi) statistical data analysis. IHC has the advantage to preserve tissue morphology and thus antigen location at histological and cell levels. By simultaneously processing thousands of samples, the technology allows standardized screening of protein expression using IHC and thus provides a very efficient way for biomarker validation. Slide scanning and image analysis enable archiving, sharing and quantitative staining characterization. Finally, data analysis enables biomarkers to be statistically validated and compared. This technology can be provided as a service to companies and research centers. The SME is also interested in joint research programs. Services agreement or subcontracting can be considered.