Summary:
A Korean R&D institute specialised in ICT bio-healthcare has developed an automated biomarker analysis technology, enabling to diagnose cardiovascular disease in the early stage. The technology is more reliable than existing strip-type diagnostic kit and enables diagnostic devices to be miniaturised compared to conventional devices. Any organisation in need of such a technology can be a partner under technical cooperation and research cooperation agreement.
Description:
To diagnose the cardiovascular disease, biomarker-based cardiovascular disease test has normally taken by large medical equipment using ELISA (Enzyme-linked immunosorbent assay) in hospitals or a strip-type diagnostic kit.
However, the result obtained from strip-type diagnostic kit shows low reliability and small, medium-sized hospitals or healthcare centres most visited by patients do not have automatic immunological diagnostic device that accurately detect cardiovascular disease biomarkers in the early stage.
A Korean R&D institute focusing on ICT Bio-healthcare has developed automatic biomarker analysis technology that diagnoses cardiovascular disease simply and accurately as a Point-of-Care.
An automatic analysis device with the technology is microwave-sized, smaller than existing devices. It also takes less than 15 minutes to analyse 5 different biomarkers simultaneously including pre-treatment process of sample and shows high accuracy level of results.
The technology invokes the principle that a high-density antibody fixed to the surface of the biochip catches the biomarker in the blood plasma and detects the biomarker as light in specific wavelength, and consists of three specific technologies as below.
1) Signal amplification technology: amplifies the signal, helping in observing light signals generated from antigen-antibody reaction in order to increase the reliability of detecting biomarkers.
2) High-density antibody fixation technology: enables low-concentration protein which is not easily observed to be detected.
3) Rotational motion-based automation technology: minimises the distances among centrifugation, blood sample and mixing for the pre-treatment process.
On-site Point-of-Care test device using this technology can not only screen patients with cardiovascular disease easily but predict prospective cardiovascular disease. Thus, it is expected to be used for cardiovascular disease as well as chronic disease and obesity, resulting in improving medical services.
The Korean R&D institute is looking for companies or research institutes engaged in medical diagnostic device can be the main partners to improve their products under technical agreement. Also, this institute is interested in applying joint R&D programme(e.g. EUREKA, EUROSTARS) to develop point-of-care medical devices for diagnostics of cancer, virus, and food poisoning under research cooperation agreement.
Type (e.g. company, R&D institution…), field of industry and Role of Partner Sought:
Type of partner sought: SMEs or research institute
- Specific area of activity of the partner: medical diagnostic device manufacturing
- Task to be performed: Employing the technology to improve the existing medical diagnostic devices. Applying to joint R&D programme(e.g. EUREKA, EUROSTARS) to develop point-of-care medical devices for diagnostics of cancer, virus, and food poisoning.
Stage of Development:
Available for demonstration
IPR Status:
Patents granted
Comments Regarding IPR Status:
Patents in USA and South Korea
External code:
TOKR20210115004
